Atlas Labs Bio products are sold for laboratory research use only — not for human or animal consumption, and not intended to diagnose, treat, cure, or prevent any disease. Must be handled only by qualified researchers, in accordance with all applicable laws. See the full Research Disclaimer page for complete terms.
GHK-Cu
≥98% Purity Research Use OnlyPrice range: $24.99 through $44.99
GHK-Cu is the copper(II) complex of the naturally occurring tripeptide glycyl-L-histidyl-L-lysine (GHK), studied extensively in cell culture and preclinical models. Supplied as a lyophilized powder for laboratory research use only.
Description
What is GHK-Cu?
GHK-Cu, also called copper tripeptide-1, is the complex formed between copper(II) and the tripeptide glycyl-L-histidyl-L-lysine (CAS 49557-75-7, molecular formula C14H22CuN6O4, molecular weight 401.9 g/mol). GHK occurs naturally in human plasma and has a copper affinity similar to the copper transport site on albumin.[1]
Research background
GHK-Cu has a long research history in fibroblast cell culture and rodent models. Published studies have examined its effect on matrix metalloproteinase-2 expression in fibroblast cultures[2] and on connective tissue accumulation in experimental wound models in rats.[3] A 2018 review discusses GHK in the context of gene expression data.[4]
Format and documentation
Atlas Labs Bio supplies GHK-Cu as a blue to blue-violet lyophilized powder (the color comes from the bound copper) in sealed glass vials at 50 mg and 100 mg. Every batch is tested by an independent third-party laboratory, and the certificate of analysis for the batch currently shipping is linked on this page and in the COA Library.
Storage: Store at 2-8°C.
Frequently asked questions
Why is GHK-Cu blue?
The blue to blue-violet color comes from the copper(II) ion bound to the GHK peptide.
What is the difference between GHK and GHK-Cu?
GHK is the tripeptide on its own. GHK-Cu is GHK bound to a copper(II) ion.[1]
What is the CAS number for GHK-Cu?
49557-75-7.
Can GHK-Cu be used by people?
No. Atlas Labs Bio products are sold strictly for laboratory research use and are not for human or animal consumption.
References
- “The human tri-peptide GHK and tissue remodeling.” Journal of Biomaterials Science, Polymer Edition, 2008. PMID 18644225.
- “The tripeptide-copper complex glycyl-L-histidyl-L-lysine-Cu2+ stimulates matrix metalloproteinase-2 expression by fibroblast cultures.” Life Sciences, 2000. PMID 11045606.
- “In vivo stimulation of connective tissue accumulation by the tripeptide-copper complex glycyl-L-histidyl-L-lysine-Cu2+ in rat experimental wounds.” Journal of Clinical Investigation, 1993. PMID 8227353.
- “Regenerative and Protective Actions of the GHK-Cu Peptide in the Light of the New Gene Data.” International Journal of Molecular Sciences, 2018. PMID 29986520.
Additional information
| Strength | 50 mg, 100 mg |
|---|
Properties
- CAS Number
- 49557-75-7
- Synonyms
- Copper tripeptide-1, Copper peptide GHK-Cu, Glycyl-L-histidyl-L-lysine copper(II), Cu-GHK
- Molecular Formula
- C14H22CuN6O4
- Molecular Weight
- 401.9 g/mol
- Physical Appearance
- Blue to blue-violet lyophilized powder
- Terms
- Atlas Labs Bio products are sold for laboratory research use only — not for human or animal consumption, and not intended to diagnose, treat, cure, or prevent any disease. Must be handled only by qualified researchers, in accordance with all applicable laws. See the full Research Disclaimer page for complete terms.
Certificate Of Analysis
Current Batch
Select a strength above to view its Certificate of Analysis.
2D Structure
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