Atlas Labs Bio products are sold for laboratory research use only — not for human or animal consumption, and not intended to diagnose, treat, cure, or prevent any disease. Must be handled only by qualified researchers, in accordance with all applicable laws. See the full Research Disclaimer page for complete terms.
Retatrutide
≥98% Purity Research Use OnlyPrice range: $69.99 through $169.99
Retatrutide (LY3437943) is a synthetic peptide described in the literature as a single-molecule agonist at the GIP, GLP-1 and glucagon receptors. Supplied as a lyophilized powder for laboratory research use only.
Description
What is retatrutide?
Retatrutide, also referenced by its development code LY3437943, is a synthetic peptide (CAS 2381089-83-2, molecular formula C221H342N46O68, molecular weight 4731.4 g/mol). It is described in the published literature as a triple agonist: one peptide with activity at the glucose-dependent insulinotropic polypeptide receptor (GIPR), the glucagon-like peptide-1 receptor (GLP-1R) and the glucagon receptor (GCGR).[1]
Research background
The discovery and receptor pharmacology of LY3437943 were described in Cell Metabolism in 2022, covering its activity at each of the three receptors in cell-based assays and its characterization in preclinical models.[1] Retatrutide remains an investigational compound. Its activity has also been examined in isolated human atrial tissue preparations in vitro.[2]
Format and documentation
Atlas Labs Bio supplies retatrutide as a white to off-white lyophilized powder in sealed glass vials at 10 mg, 20 mg and 30 mg. Every batch is tested by an independent third-party laboratory, and the certificate of analysis for the batch currently shipping is linked on this page and in the COA Library.
Storage: Store at 2-8°C.
Frequently asked questions
What is the CAS number for retatrutide?
2381089-83-2. It is also referenced in the literature as LY3437943.
What receptors does retatrutide act on?
It is described in published research as an agonist at the GIP, GLP-1 and glucagon receptors.[1]
Is a certificate of analysis available?
Yes. The COA for the batch currently shipping is linked on this page and in the COA Library.
Can retatrutide be used by people?
No. Atlas Labs Bio products are sold strictly for laboratory research use and are not for human or animal consumption.
References
- “LY3437943, a novel triple glucagon, GIP, and GLP-1 receptor agonist for glycemic control and weight loss: From discovery to clinical proof of concept.” Cell Metabolism, 2022. PMID 35985340.
- “Inotropic effects of retatrutide in isolated human atrial preparations.” Naunyn-Schmiedeberg’s Archives of Pharmacology, 2025. PMID 40613938.
Additional information
| Strength | 10 mg, 20 mg, 30 mg |
|---|
Properties
- CAS Number
- 2381089-83-2
- Synonyms
- LY3437943, GGG tri-agonist, GLP-1/GIP/glucagon receptor triagonist
- Molecular Formula
- C221H342N46O68
- Molecular Weight
- 4731.4 g/mol
- Physical Appearance
- White to off-white lyophilized powder
- Terms
- Atlas Labs Bio products are sold for laboratory research use only — not for human or animal consumption, and not intended to diagnose, treat, cure, or prevent any disease. Must be handled only by qualified researchers, in accordance with all applicable laws. See the full Research Disclaimer page for complete terms.
Certificate Of Analysis
Current Batch
Select a strength above to view its Certificate of Analysis.
Related products
-
≥98% Purity
-
≥98% Purity
-
≥98% Purity
KPV
Price range: $27.99 through $42.99Select options This product has multiple variants. The options may be chosen on the product page -
≥98% Purity
Reviews
There are no reviews yet.