Atlas Labs Bio products are sold for laboratory research use only — not for human or animal consumption, and not intended to diagnose, treat, cure, or prevent any disease. Must be handled only by qualified researchers, in accordance with all applicable laws. See the full Research Disclaimer page for complete terms.
5-Amino-1MQ
≥98% Purity Research Use Only$59.99
5-Amino-1MQ (5-amino-1-methylquinolinium) is a small-molecule inhibitor of the enzyme nicotinamide N-methyltransferase (NNMT). Supplied as a powder for laboratory research use only.
Description
What is 5-Amino-1MQ?
5-Amino-1MQ, or 5-amino-1-methylquinolinium (CAS 42464-96-0, molecular formula C10H11N2, molecular weight 159.21 g/mol), is a small molecule rather than a peptide. It is described in the literature as a potent inhibitor of nicotinamide N-methyltransferase (NNMT).[1]
Research background
5-Amino-1MQ has been studied in rodent research. A validated LC-MS/MS method for measuring it in rat plasma has been published and applied to pharmacokinetic and oral bioavailability studies in rats.[1]
Format and documentation
Atlas Labs Bio supplies 5-Amino-1MQ as a white to off-white powder in a 50 mg vial. Third-party certificates of analysis for Atlas Labs Bio products are published in the COA Library.
Storage: Store at 2-8°C.
Frequently asked questions
Is 5-Amino-1MQ a peptide?
No. It is a small-molecule quinolinium compound.
What enzyme does 5-Amino-1MQ inhibit?
Nicotinamide N-methyltransferase (NNMT).[1]
Can 5-Amino-1MQ be used by people?
No. Atlas Labs Bio products are sold strictly for laboratory research use and are not for human or animal consumption.
References
- “Development & validation of LC-MS/MS assay for 5-amino-1-methyl quinolinium in rat plasma: Application to pharmacokinetic and oral bioavailability studies.” Journal of Pharmaceutical and Biomedical Analysis, 2021. PMID 34304009.
Properties
- CAS Number
- 42464-96-0
- Synonyms
- 5-Amino-1-methylquinolinium, NNMT inhibitor
- Molecular Formula
- C10H11N2
- Molecular Weight
- 159.21 g/mol
- Physical Appearance
- White to off-white lyophilized powder
- Terms
- Atlas Labs Bio products are sold for laboratory research use only — not for human or animal consumption, and not intended to diagnose, treat, cure, or prevent any disease. Must be handled only by qualified researchers, in accordance with all applicable laws. See the full Research Disclaimer page for complete terms.
Certificate Of Analysis
Current Batch
The certificate of analysis for the current batch is being prepared and will be published here.
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